DeCS

Descriptor English:

Off-Label Use

Descriptor Spanish:

Uso Fuera de lo Indicado

Spanish from Spain

Descriptor	prescripción en indicaciones no aprobadas
Entry term(s)	empleo de medicamentos para indicaciones no aprobadas empleo extraoficial empleo no indicado en el prospecto uso de fármacos con ahorro de dosis uso de fármacos en dosis fraccionadas uso de fármacos en dosis reducidas uso extraoficial usos de fármacos con ahorro de dosis usos de fármacos en dosis reducidas
Scope note:	Práctica de prescribir o de utilizar un medicamento o una vacuna fuera del ámbito de las indicaciones especificadas en la ficha técnica oficial aprobada por las autoridades sanitarias para el tratamiento de una enfermedad o afección concretas.

Descriptor Portuguese:

Uso Off-Label

Descriptor French:

Utilisation hors indication

Entry term(s):

Dose Sparing Drug Use
Dose-Sparing Drug Use
Dose-Sparing Drug Uses
Fractional Dose Drug Use
Indication, Unlabeled
Off Label Prescribing
Off Label Use
Off-Label Prescribing
Off-Label Prescribings
Off-Label Uses
Prescribing, Off-Label
Reduced Dose Drug Use
Reduced-Dose Drug Use
Reduced-Dose Drug Uses
Unlabeled Indication
Unlabeled Indications

Tree number(s):

E02.319.307.500

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D056687

Scope note:

The practice of prescribing or using a drug or a vaccine outside the scope of the drug's official approved label as designated by a regulatory agency concerning the treatment of a particular disease or condition.

Annotation:

do not confuse with DRUG REPOSITIONING

Allowable Qualifiers:

CL classification
EC economics
ES ethics
HI history
LJ legislation & jurisprudence
NU nursing
SN statistics & numerical data
ST standards
VE veterinary

Previous Indexing:

Drug Labeling (2008-2009)
Drug Prescriptions (2008-2009)

Public MeSH Note:

2010

History Note:

2010

Drug Approval MeSH
Drug Labeling MeSH
Drug Utilization MeSH

DeCS ID:

53689

Unique ID:

D056687

Documents indexed in the Virtual Health Library (VHL):

Click here to access the VHL documents

Date Established:

2010/01/01

Date of Entry:

2009/07/06

Revision Date:

2018/02/06

ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT

Therapeutics [E02]

Therapeutics

Drug Therapy [E02.319]

Drug Therapy

Drug Prescriptions [E02.319.307]

Drug Prescriptions

Drug Substitution [E02.319.307.312]

Drug Substitution

Off-Label Use [E02.319.307.500]

Off-Label Use

Off-Label Use - Preferred

Concept UI	M0528564
Scope note	The practice of prescribing or using a drug or a vaccine outside the scope of the drug's official approved label as designated by a regulatory agency concerning the treatment of a particular disease or condition.
Preferred term	Off-Label Use
Entry term(s)	Indication, Unlabeled Off Label Prescribing Off Label Use Off-Label Prescribing Off-Label Prescribings Off-Label Uses Prescribing, Off-Label Unlabeled Indication Unlabeled Indications

Fractional Dose Drug Use - Narrower

Concept UI	M000639537
Preferred term	Fractional Dose Drug Use
Entry term(s)	Dose Sparing Drug Use Dose-Sparing Drug Use Dose-Sparing Drug Uses Reduced Dose Drug Use Reduced-Dose Drug Use Reduced-Dose Drug Uses

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